apl

Preclinical studies suggest that As 2 O 3 induces apoptosis and possibly differentiation in APL cells.

新近研究表明,As2O3不仅对APL细胞,而且对其它许多实体癌细胞均具有诱导凋亡作用.

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Conclusion Chromosome painting and RT-PCR are reliable methods for characterization of the insertion involving chromosomes 15 and 17 in APL patients.

结论染色体涂染和逆转录-PCR技术是明确急性早幼粒细胞白血病患者涉及15和17号染色体插入易位的可靠手段。

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Conclusion There are significant improvement in prognosis of APL treated with ATRA.

结论全反式维甲酸对急性早幼粒细胞性白血病患者的预后有很大改善.

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Recently, similar cases have also been found in Caucasian APL.

近来在白种人APL中发现了具有t( 11;17)的病例.

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APL ( average product length) is proposed as the criterion for measuring control chart performance to study the optimal design of skewed control chart.

以平均产品长度（APL）为评价控制图性能的标准，研究了偏态控制图的优化设计问题。

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The TM transcription and expression upregulated by ATRA may alleviate dysfunction of coagulation in APL.

ATRA增高TM转录及表达,缓解APL患者凝血功能异常.

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APL-wrapped version of the system from where the daily operation of bear out my own value.

APL被迫换版编制堵住在这些边际的常日运作证实了自己的代价.

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Recent clinical studies show that arsenic trioxide ( As 2O 3) and arsenic tetrasulfide ( As 4S 4) are effective in the treatment to acute promyelocytic leukemia ( APL).

近年来临床研究表明，三氧化二砷（As2O3）和四硫化四砷（As4S4）对急性早幼粒细胞白血病有显著的疗效；

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The positive rate of CD 15 in APL was significantly lower than those in CML-CP ( P & lt; 0.01 ).

有14.5%的APL患者 表达CD56,有48.2%的APL患者 表达CD15,CD15在APL的表达明显低于CML慢性 期( 48.2%vs95.2%,P & lt; 0.01 ).

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Methods Immunophenotype was examined by flow cytometry in 31 patients with APL.

方法采用流式细胞术检测31例APL患者的免疫表型.

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Arsenic trioxide ( As_2O_3), as an anticancer drug for the treatment of acute promyelocytic leukemia ( APL), was approved by SDA of China in 1999 and by FDA of USA in 2000.Its mechanisms of chemotherapeutic effects were very complex.

三氧化二砷（As2O3）于1999年正式通过了国家药品监督管理局的审批，并于2000年9月25日作为治疗急性早幼粒细胞白血病（APL）的新药通过FDA的审批。

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In contrast, APL cells of two cases showed synergistic differentiation after treatment with ATAR and bufalin.

为了进一步研究蟾蜍灵对ATRA诱导分化的增强效应, 我们研究蟾蜍灵与维甲酸联合对APL原 代培养细胞的诱导分化作用.

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The change and significance of pml/ rar α fusion gene of the long-term survival APL

长期生存的急性早幼粒细胞白血病PML/RARα融合基因的变化及意义

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Average production length ( APL) is introduced as the criterion for measuring control scheme performance. A model is developed with sampling rate and maximum false alarm rate as inputs to determine the optimum subgroup size and control limits as measured by APL.

本文以平均运行长度（APL）为衡量控制图有效性的标准，以抽样比例和最大可接受错误报警率为输入，通过建立模型的方法，确定最佳的样本容量和控制线参数。

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Conclusions: There are differences in the types of APL antibodies between auto-immune diseases and infectious diseases.

梅毒和SLE患者总阳性率与正常人相比显著升高。结论：自身免疫性疾病患者的抗磷脂抗体与感染时有所不同；

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Exhibits: Continuous Annealing and Pickling Line for Stainless Steel Strips ( APL); Continuous Bright Annealing Line for Stainless Steel Strips. ( BAL)

展品：用于带钢加工的机械设备和生产线（连续酸洗退火、连续光亮退火等）。

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No, not that particularly. Other language perhaps more so, I started with APL.

他语言也许更明显些，我最先学的APL

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Objective To observe the clinical effects of all-trans-retinoic acid ( ATRA ) in treating 11 patients with acute promyelocytic leukemia ( APL ).

目的观察11例急性早幼粒细胞性白血病患者经全反式 维 甲酸 治疗后的临床效果.

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Objective : To detect the mechanism of hyperleukocytosis in patients with APL after treatment with ATRA.

目的: 揭示APL患者ATRA治疗后高白细胞征的机制.

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Method: The PML-RAR α fused protein in APL patients was stained by immuno-fluorescence antibody for PML.

方法: 采用免疫荧光技术检测APL患者PML-RARα融合蛋白.

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Anaerobes isolated form anaerobic culture were identified using APl 20A System.

应用API20A鉴定系统对分离到的厌氧菌菌种进行鉴定。

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Methods : The clinical information of 62 patients with newly diagnosed APL was retrospectively analyzed.

方法回顾性分析62例初诊的APL患者的临床资料.

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This is Jason Stone from APL Corporation.

我是APL公司 的贾森·斯通.

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Objective: To investigate the new maintenance chemotherapy of acute promyelocytic leukemia ( APL) after complete remission by all-trans retinoic acid ( ATRA), thereby increasing the long disease-free survival time of APL.

目的探索急性早幼粒细胞白血病（APL）经全反式维甲酸（ATRA）治疗达完全缓解（CR）后理想的维持治疗方案，提高APL的长期无病生存时间。

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METHODS: Twenty_five relapsed APL patients were enrolled ( M 15, F 10, 34 a ± s 12 a), 10 mL of 0.1% arsenous acid solution+ 5% glucose 500 mL was injected iv, drip, daily for 28_56 d.

方法：复发的急性早幼粒细胞白血病25例（男性15例，女性10例；年龄34a±s12a）以亚砷酸10mg／d＋5%葡萄糖注射液500mL静脉滴注，28～56d为一个疗程。

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IntroductionAll-trans retinoic acid ( ATRA ) is efficiently differentiation in-ducer for acute promyelocytic leukemia ( APL ).

全反式维甲酸 ( ATRA ) 用于急性早幼粒细胞白血病 ( APL) 的诱导分化治疗,有很高的完全缓解(CR ) 率,现已成为APL诱导缓解治疗的首选药物.

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Methods Analyzing clinical data of 18 patients with APL.

方法　分析18例APL患者的临床资料.

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Terminal Differentiation of Human Acute Promyelocytic Leukemia ( APL) Cells Induced by Tanshinone ⅱ A in Primary Culture

丹参酮ⅡA诱导原代培养人急性早幼粒细胞白血病细胞分化

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ATRA treatment induce terminal differentiation and growth arrest of several established human myeloid cell lines in vitro and has also proven to be effective in the clinical treatment of acute promyelocytic leukemia ( APL) by inducing differentiation and apoptosis of the immature blasts.

在体外一些髓样细胞系中ATRA可以诱导细胞周期阻滞及启动终末分化。并且由于它的这一特性已在临床用于治疗急性早幼粒细胞性白血病，并取得很好的疗效。

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The Effects of Arginase on Human Primary APL Cell's Growth and Differentiation

精氨酸酶对人APL原代细胞生长和分化的影响

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