The main character of the diseases is the deposition of extra-cellular matrix ( ECM) because of its excess synthesis and decreased degradation.

  • 其主要特征表现为以胶原为主要成分的细胞外基质(extra-cellular matrix,ECM)合成增多、降解相对不足而过量沉积。
  • 来源:互联网摘选2026-05-07 13:41:54

  • 重点词汇
  • degradationn.堕落;潦倒;毁坏;恶化;
  • because of因为,由于;基于;
  • ofprep. 关于;属于…的;由…制成;
  • decreasedv.(使)缩短,减小,减少( decrease的过去式和过去分词 );
  • excessn.超过;超额量;多余量;放肆;
  • theart.这个;指已提到或易领会到的人或事物;指独一无二的、正常的或不言而喻的人或事物;用以泛指;与形容词连用,指事物或统称的人;用于姓氏的复数形式前,指家庭或夫妇;(指特定用途的事物)足够,恰好;每,一;当前的,本,此;(重读,表示所指的为知名或重要的人或事物)
  • andconj. 和;与;而且;于是;然后
  • depositionn.沉积(物);[律](在法庭上的)宣誓作证,证词;免职,革职;
  • main character[医]主要性状;
  • 相关例句
1、

To examine changes of collagen network and Matrix Metaloproteinases ( MMPs) activity in hypertrophied rat myocardium.

探讨压力负荷增高性心肌肥厚时心肌胶原网络及心肌细胞外基质金属蛋白酶(MMPs)活性的变化。

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2、

The PAI-1 expression and deposition of extracellular matrix in renal tissue significantly decreased ( P < 0.05).

肾组织细胞外基质的沉积明显减少及肾组织PAI-1的表达降低(P

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3、

Type I collagen is a major constituent of extracellular matrix produced when fibrogenesis and its expression is controlled by transcription and post-transcriptional.

I型胶原是纤维化中细胞外基质(ECM)的主要成分之一,其表达受转录、转录后水平多重调控。

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4、

Conclusion: Zymography is suitable for the studies on the role of HSC in the regulation of extracellular matrix turnover.

结论:酶谱法是研究HSC调节肝纤维化过程中细胞外基质(ECM)代谢的有效手段。

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5、

Conclusion Co-culture of cryopreserved rat islets with SIS can increase the recovery of islet cells and improve their function.

结论SIS作为一种天然的细胞外基质材料,可显著提高胰岛细胞冷冻保存后的回收率,减少冻存胰岛细胞复苏时的死亡,并改善胰岛细胞的功能。

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6、

A Clinical Study on the Saikosaponin on FSC Activation and Extracellular Matrix Synthesis

柴胡皂甙对FSC激活及合成细胞外基质的实验研究

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7、

The pathological foundation of liver fibrosis includes the increased synthesis and decreased degradation of extracellular matrix ( ECM), which leads the excessive deposition of collagen.

肝纤维化的病理学基础为细胞外基质(Extracellular matrix,ECM)合成增加,降解减少,导致胶原过度沉积。

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8、

The expressions of TGF β 1 and extracellular matrix protein and TGF β 1mRNA were analyzed by immunohistochemistry and in situ hybridization.

用免疫组化及原位杂交观察肾脏TGFβ1表达及细胞外基质(ECM)沉积。以计算机图象分析进行半定量比较。

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9、

Objective: To investigate the expression and significance of extracellular matrix protein 1 ( ECM1) in tumor tissues.

目的:探讨细胞外基质蛋白1(extracellular matrix protein1,ECM1)在肿瘤组织中的表达及意义。

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10、

Matrix metalloproteinases ( MMPs), zinc dependent proteolytic enzymes, can cleave extracellular matrix ( ECM).

基质金属蛋白酶(MMPs)是一大类锌依赖性内肽酶家族,能降解一种或几种细胞外基质(ECM)。

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11、

The Inhibitive Effects and Mechanisms of PPAR γ 1 on the Extracellular Matrix of Mesangial Cells

PPARγ1对系膜细胞外基质生成的抑制作用及其机制

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12、

Electron microscope showed that thickness of glomerular basement membrane and mesangial cells were normal, capillary lumen was open in Group NC, but mesangial proliferation;

电镜显示NC组大鼠肾小球细胞外基质与系膜细胞分布正常,毛细血管腔开放;

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13、

Hepatic fibrosis is caused by an imbalance between the synthesis and degradation of extracellular matrix ( ECM), which leads to its excessive deposition.

肝纤维化是由于肝脏胶原等细胞外基质(extracellular matrix ECM)合成与降解失衡,导致在肝内过量沉积。

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14、

Effect of integrin α_V β_3 on expression and activation of matrix metalloproteinase-2 of human melanoma cells regulated by extracellular matrix

整合素αVβ3在细胞外基质调控人黑色素瘤MMP-2表达和活化中的作用

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15、

Many studies displayed that degradation of extracellular matrix ( ECM) was the capital step in the process of tumor invasion and metastasis.

大量研究显示,细胞外基质(extracellular matrix ECM)的降解是肿瘤侵袭和转移过程中关键的一步。

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16、

The accumulation of extracellular matrix ( ECM) resulting from the unbalance of synthesis and degradation is the main cause of TIF.

细胞外基质(extracellular matrix ECM)合成和降解失衡,造成大量积聚是引起肾间质纤维化的主要原因。

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17、

Objective To evaluate the role of extracelluar matrix ( ECM) in aging rat lungs.

目的观察细胞外基质(ECM)在肺老化中的作用。

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18、

Effect of Shen Luo-ning on Extracellular Matrix Metabolism of Kidney Interstitial Tissue in IgA Nephrosis Rats

肾络宁对IgA肾病大鼠肾间质细胞外基质代谢的影响

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19、

Extracellular matrix ( ECM) accumulation is the final pathway to renal fibrosis.

细胞外基质(ECM)积聚是肾脏纤维化的最终途径。

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20、

Matrix metalloproteinases ( MMPs) is a main enzyme to degrade extracelluar matrix.

基质金属蛋白酶家族(Matrix metalloproteinases,MMPs)是降解细胞外基质的主要酶类之一。

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